AJCC 7thに従ってUICC 7thの訂正が行われている
(2011年05月)
pT1: ≤ 1 mm in thickness
pT1a: Clark level II-III, without ulceration
→訂正版:≤ 1.0 mm in thickness
かつ潰瘍なし,分裂像 1/mm2 未満
pT1b: Clark level IV-V, or with ulceration
→訂正版: 潰瘍または1/mm2以上の分裂像が存在
pT2: > 1mm and ≤ 2 mm;
pT3: > 2 mm and ≤ 4 mm;
pT4: > 4 mm
pT2a: ulcer (-); pT2b: ulcer (+)
pT3a: ulcer (-); pT3b: ulcer (+)
pT4a: ulcer (-); pT4b: ulcer (+)
N1a: microscopic single node metastasis
N1b: macroscopic single lymph node
N2a: 2-3 microscopic
N2b: 2-3 macroscopic
N2c: satellite or in-transit* metasitasis without nodal
metastasis
*in-transit metastasis is skin involment more than 2 cm from
the
primary tumor; saetllites are tumor cells ≤ 2 cm
N3: ≥ 4 nodes, or satellite, or in-transit and lymph node
metastasis
M1a: skin or lymph node beyond regional LN
M1b: lung
M1c: any other sites, or any sites with elevated LDH
Stage 0 pTis
Stage IA
Stage IB pT1b or pT2a
Stage IIA pT2b or pT3a
Stage IIB pT3b or pT4a
Stage IIC pT4b
Stage III N1-3 (IIIA, TaN1a2a; IIIB, TaN1b2bc
or
TbN1a2ac; IIIC, TbN1b2b or N3)
Stage IV M1
--
TNM of Paget disease
(1) MPD without invasive carcinoma on histologic examination
is
classified as carcinoma in situ (Tis). MPD with a contiguous or
non-contiguous invasive component on histology is staged
according
to
the invasive component using the guidelines for staging of
breast
carcinoma.
(2) Primary EMP is staged either according to the FIGO
(Fédération
Internationale de Gynécologie et d’Obstétrique) or
the TNM system of
the AJCC (American Joint Committee on Cancer)
for vulvar tumours.
(3) Secondary EMP is staged according to the criteria
for the
associated internal malignancy.
参考:Clark's level (使われなくなった)
I: in situ (pTis: atypical melanocytic hyperplasia,
severe melanocytic
dysplasia, not an invasive malignant lesion)
II: papillary dermis
III: pushin' reticular
IV: reticular dermis
V: subcutis
reticular dermisはreticular fiberが多い