Head and Neck Tumours (WHO/IARC腫瘍分類 第4版 第9巻による)
1. Tumours of the nasal cavity, paranasal sinuses and skull base
Carcinomas
Keratinizing squamous cell carcinoma
Non-keratinizing squamous cell carcinoma
Spindle cell (sarcomatoid) squamous cell carcinoma
Lymphoepithelial carcinoma
Sinonasal undifferentiated carcinoma
NUT carcinoma
Neuroendocrine carcinoma
Adenocarcinoma
Intestinal-type adenocarcinoma
Non–intestinal-type adenocarcinoma
Teratocarcinosarcoma
Sinonasal papillomas
Sinonasal papilloma, inverted type
Sinonasal papilloma, oncocytic type
Sinonasal papilloma, exophytic type
Respiratory epithelial lesions
Respiratory epithelial adenomatoid hamartoma
Seromucinous hamartoma
Salivary gland tumours
Pleomorphic adenoma
Malignant soft tissue tumours
Fibrosarcoma
Undifferentiated pleomorphic sarcoma
Leiomyosarcoma
Rhabdomyosarcoma
Angiosarcoma
Malignant peripheral nerve sheath tumour
Biphenotypic sinonasal sarcoma
Synovial sarcoma
Borderline / low-grade malignant soft tissue tumours
Desmoid-type fibromatosis
Sinonasal glomangiopericytoma
Solitary fibrous tumour
Epithelioid haemangioendothelioma
Benign soft tissue tumours
Leiomyoma
Haemangioma
Schwannoma
Neurofibroma
Other tumours
Meningioma
Sinonasal ameloblastoma
Chondromesenchymal hamartoma
Haematolymphoid tumours
Extranodal NK/T-cell lymphoma
Extraosseous plasmacytoma
Neuroectodermal / melanocytic tumours
Ewing sarcoma/primitive neuroectodermal tumours
Olfactory neuroblastoma
Mucosal melanoma
2. Tumours of the nasopharynx
Nasopharyngeal carcinoma
Nasopharyngeal papillary adenocarcinoma
Salivary gland tumours
Adenoid cystic carcinoma
Salivary gland anlage tumour
Benign and borderline lesions
Hairy polyp
Ectopic pituitary adenoma
Craniopharyngioma
Soft tissue tumours
Nasopharyngeal angiofibroma
Haematolymphoid tumours
Notochordal tumours
Chordoma
3. Tumours of the hypopharynx, larynx, trachea and parapharyngeal space
Malignant surface epithelial tumours
Conventional squamous cell carcinoma
Verrucous squamous cell carcinoma
Basaloid squamous cell carcinoma
Papillary squamous cell carcinoma
Spindle cell squamous cell carcinoma
Adenosquamous carcinoma
Lymphoepithelial carcinoma
Precursor lesions
Dysplasia
Squamous cell papilloma & squamous cell papillomatosis
Neuroendocrine tumours
Well-differentiated neuroendocrine carcinoma
Moderately differentiated neuroendocrine carcinoma
Poorly differentiated neuroendocrine carcinoma
Salivary gland tumours
Adenoid cystic carcinoma
Pleomorphic adenoma
Oncocytic papillary cystadenoma
Soft tissue tumours
Granular cell tumour
Liposarcoma
Inflammatorymyofibroblastictumour
Cartilage tumours
Chondroma and chondrosarcoma
Haematolymphoid tumours
4. Tumours of the oral cavity and mobile tongue
Malignant surface epithelial tumours
Squamous cell carcinoma
Oral potentially malignant disorders & oral epithelial dysplasia
Oral potentially malignant disorders
Oral epithelial dysplasia
Proliferative verrucous leukoplakia
Papillomas
Squamous cell papilloma
Condyloma acuminatum
Verruca vulgaris
Multifocal epithelial hyperplasia
Tumours of uncertain histogenesis
Congenital granular cell epulis
Ectomesenchymal chondromyxoid tumour
Soft tissue and neural tumours
Granular cell tumour
Rhabdomyoma
Lymphangioma
Haemangioma
Schwannoma and neurofibroma
Kaposi sarcoma
Myofibroblastic sarcoma
Oral mucosal melanoma
Salivary type tumours
Mucoepidermoid carcinoma
Pleomorphic adenoma
Haematolymphoid tumours
CD30-positive T-cell lymphoproliferative disorder
Plasmablastic lymphoma
Langerhans cell histiocytosis
Extramedullary myeloid sarcoma
5. Tumours of the oropharynx (base of tongue, tonsils, adenoids)
Squamous cell carcinoma
Squamous cell carcinoma, HPV-positive
Squamous cell carcinoma, HPV-negative
Salivary gland tumours
Pleomorphic adenoma
Adenoid cystic carcinoma
Polymorphous adenocarcinoma
Haematolymphoid tumours
Hodgkin lymphoma
Burkitt lymphoma
Follicular lymphoma
Mantle cell lymphoma
T-lymphoblastic leukaemia/lymphoma
Follicular dendritic cell sarcoma
6. Tumours and tumour-like lesions of the neck and lymph nodes
Tumours of unknown origin
Carcinoma of unknown primary
Merkel cell carcinoma
Heterotopia-associated carcinoma
Haematolymphoid tumours
Cysts and cyst-like lesions
Branchial cleft cyst
Thyroglossal duct cyst
Ranula
Dermoid and teratoid cysts
7. Tumours of salivary glands
Malignant tumours
Mucoepidermoid carcinoma
Adenoid cystic carcinoma
Acinic cell carcinoma
Polymorphous adenocarcinoma
Clear cell carcinoma
Basal cell adenocarcinoma
Intraductal carcinoma
Adenocarcinoma, NOS
Salivary duct carcinoma
Myoepithelial carcinoma
Epithelial–myoepithelial carcinoma
Carcinoma ex pleomorphic adenoma
Secretory carcinoma
Sebaceous adenocarcinoma
Carcinosarcoma
Poorly differentiated carcinoma
Lymphoepithelial carcinoma
Squamous cell carcinoma
Oncocytic carcinoma
Sialoblastoma
Benign tumours
Pleomorphic adenoma
Myoepithelioma
Basal cell adenoma
Warthin tumour
Oncocytoma
Lymphadenoma
Cystadenoma
Sialadenoma papilliferum
Ductal papillomas
Sebaceous adenoma
Canalicular adenoma and other ductal adenomas
Non-neoplastic epithelial lesions
Sclerosing polycystic adenosis
Nodular oncocytic hyperplasia
Lymphoepithelial sialadenitis
Intercalated duct hyperplasia
Benign soft tissue lesions
Haemangioma
Lipoma/sialolipoma Nodular fasciitis
Haematolymphoid tumours
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma)
8. Odontogenic and maxillofacial bone tumours
Odontogenic carcinomas
Ameloblastic carcinoma
Primary intraosseous carcinoma, NOS
Sclerosing odontogenic carcinoma
Clear cell odontogenic carcinoma
Ghost cell odontogenic carcinoma
Odontogenic carcinosarcoma
Odontogenic sarcomas
Benign epithelial odontogenic tumours
Ameloblastoma
Ameloblastoma, unicystic type
Ameloblastoma, extraosseous/peripheral type
Metastasizing ameloblastoma
Squamous odontogenic tumour
Calcifying epithelial odontogenic tumour
Adenomatoid odontogenic tumour
Benign mixed epithelial & mesenchymal odontogenic tumours
Ameloblastic fibroma
Primordial odontogenic tumour
Odontoma
Dentinogenic ghost cell tumour
Benign mesenchymal odontogenic tumours
Odontogenic fibroma
Odontogenic myxoma/myxofibroma
Cementoblastoma
Cemento-ossifying fibroma
Odontogenic cysts of inflammatory origin
Radicular cyst
Inflammatory collateral cysts
Odontogenic and non-odontogenic developmental cysts
Dentigerous cyst
Odontogenic keratocyst
Lateral periodontal cyst and botryoid odontogenic cyst
Gingival cysts
Glandular odontogenic cyst
Calcifying odontogenic cyst
Orthokeratinized odontogenic cyst
Nasopalatine duct cyst
Malignant maxillofacial bone and cartilage tumours
Chondrosarcoma
Mesenchymal chondrosarcoma
Osteosarcoma
Benign maxillofacial bone and cartilage tumours
Chondroma
Osteoma
Melanotic neuroectodermal tumour of infancy
Chondroblastoma
Chondromyxoid fibroma
Osteoid osteoma
Osteoblastoma
Desmoplastic fibroma
Fibro-osseous and osteochondromatous lesions
Ossifying fibroma
Familial gigantiform cementoma
Fibrous dysplasia
Cemento-osseous dysplasia
Osteochondroma
Giant cell lesions and simple bone cyst
Central giant cell granuloma
Peripheral giant cell granuloma
Cherubism
Aneurysmal bone cyst
Simple bone cyst
Haematolymphoid tumours
Solitary plasmacytoma of bone
9. Tumours of the ear
Tumours of the external auditory canal
Squamous cell carcinoma
Ceruminous adenocarcinoma
Ceruminous adenoma
Tumours of the middle and inner ear
Squamous cell carcinoma
Aggressive papillary tumour
Endolymphatic sac tumour
Otosclerosis
Cholesteatoma
Vestibular schwannoma
Meningioma
Middle ear adenoma
10. Paraganglion tumours
Carotid body paraganglioma
Laryngeal paraganglioma
Middle ear paraganglioma
Vagal paraganglioma