Soft Tissue and Bone Tumours (5th ed.)
1. Forewords and Introductions
WHO Classification of Tumours: Editorial Board
How to cite this volume
Foreword with changes from the book, including corrigenda
ICD-O coding of soft tissue and bone tumours
TNM staging of soft tissue and bone tumours
ICCR datasets: Soft tissue & bone
2. Soft tissue tumours
Soft tissue tumours: Introduction
Adipocytic tumours
Lipoma
Lipomatosis
Lipomatosis of nerve
Lipoblastoma and lipoblastomatosis
Angiolipoma
Myolipoma of soft tissue
Chondroid lipoma
Spindle cell lipoma and pleomorphic lipoma
Hibernoma
Atypical spindle cell / pleomorphic lipomatous tumour
Atypical lipomatous tumour / well-differentiated liposarcoma
Dedifferentiated liposarcoma
Myxoid liposarcoma
Pleomorphic liposarcoma
Myxoid pleomorphic liposarcoma
Fibroblastic and myofibroblastic tumours
Nodular fasciitis
Proliferative fasciitis and proliferative myositis
Myositis ossificans and fibro-osseous pseudotumour of digits
Ischaemic fasciitis
Elastofibroma
Fibrous hamartoma of infancy
Fibromatosis colli
Juvenile hyaline fibromatosis
Inclusion body fibromatosis
Fibroma of tendon sheath
Desmoplastic fibroblastoma
Myofibroblastoma
Calcifying aponeurotic fibroma
EWSR1-SMAD3-positive fibroblastic tumour (emerging)
Angiomyofibroblastoma
Cellular angiofibroma
Angiofibroma of soft tissue
Nuchal-type fibroma
Acral fibromyxoma
Gardner fibroma
Palmar fibromatosis and plantar fibromatosis
Desmoid fibromatosis
Lipofibromatosis
Giant cell fibroblastoma
Dermatofibrosarcoma protuberans
Solitary fibrous tumour
Inflammatory myofibroblastic tumour
Low-grade myofibroblastic sarcoma
Superficial CD34-positive fibroblastic tumour
Myxoinflammatory fibroblastic sarcoma
Infantile fibrosarcoma
Adult fibrosarcoma
Myxofibrosarcoma
Low-grade fibromyxoid sarcoma
Sclerosing epithelioid fibrosarcoma
So-called fibrohistiocytic tumours
Tenosynovial giant cell tumour
Deep fibrous histiocytoma
Plexiform fibrohistiocytic tumour
Giant cell tumour of soft tissue
Vascular tumours
Haemangiomas
Synovial haemangioma
Intramuscular angioma
Arteriovenous malformation/haemangioma
Venous haemangioma
Anastomosing haemangioma
Epithelioid haemangioma
Lymphangioma and lymphangiomatosis
Tufted angioma and kaposiform haemangioendothelioma
Retiform haemangioendothelioma
Papillary intralymphatic angioendothelioma
Composite haemangioendothelioma
Kaposi sarcoma
Pseudomyogenic haemangioendothelioma
Epithelioid haemangioendothelioma
Angiosarcoma
Pericytic (perivascular) tumours
Glomus tumour
Myopericytoma, including myofibroma
Angioleiomyoma
Smooth muscle tumours
Leiomyoma
EBV-associated smooth muscle tumour
Inflammatory leiomyosarcoma
Leiomyosarcoma
Skeletal muscle tumours
Rhabdomyoma
Embryonal rhabdomyosarcoma
Alveolar rhabdomyosarcoma
Pleomorphic rhabdomyosarcoma
Spindle cell / sclerosing rhabdomyosarcoma
Ectomesenchymoma
Gastrointestinal stromal tumour
Gastrointestinal stromal tumour
Chondro-osseous tumours
Soft tissue chondroma
Extraskeletal osteosarcoma
Peripheral nerve sheath tumours
Schwannoma
Neurofibroma
Perineurioma
Granular cell tumour
Dermal nerve sheath myxoma
Solitary circumscribed neuroma
Ectopic meningioma and meningothelial hamartoma
Benign triton tumour / neuromuscular choristoma
Hybrid nerve sheath tumour
Malignant peripheral nerve sheath tumour
Malignant melanotic nerve sheath tumour
Tumours of uncertain differentiation
Intramuscular myxoma
Juxta-articular myxoma
Deep (aggressive) angiomyxoma
Atypical fibroxanthoma
Angiomatoid fibrous histiocytoma
Ossifying fibromyxoid tumour
Myoepithelioma, myoepithelial carcinoma, and mixed tumour
Pleomorphic hyalinizing angiectatic tumour of soft parts
Haemosiderotic fibrolipomatous tumour
Phosphaturic mesenchymal tumour
NTRK-rearranged spindle cell neoplasm (emerging)
Synovial sarcoma
Epithelioid sarcoma
Alveolar soft part sarcoma
Clear cell sarcoma of soft tissue
Extraskeletal myxoid chondrosarcoma
Desmoplastic small round cell tumour
Extrarenal rhabdoid tumour
PEComa
Intimal sarcoma
Undifferentiated sarcoma
3. Undifferentiated small round cell sarcomas of bone and soft tissue
Ewing sarcoma
Round cell sarcoma with EWSR1-non-ETS fusions
CIC-rearranged sarcoma
Sarcoma with BCOR genetic alterations
4. Bone tumours
Bone tumours: Introduction
Chondrogenic tumours
Subungual exostosis
Bizarre parosteal osteochondromatous proliferation
Periosteal chondroma
Enchondroma
Osteochondroma
Chondroblastoma
Chondromyxoid fibroma
Osteochondromyxoma
Synovial chondromatosis
Central atypical cartilaginous tumour / chondrosarcoma, grade 1
Secondary peripheral atypical cartilaginous tumour / chondrosarcoma, grade 1
Central chondrosarcoma, grades 2 and 3
Secondary peripheral chondrosarcoma, grades 2 and 3
Periosteal chondrosarcoma
Clear cell chondrosarcoma
Mesenchymal chondrosarcoma
Dedifferentiated chondrosarcoma
Osteogenic tumours
Osteoma
Osteoid osteoma
Osteoblastoma
Low-grade central osteosarcoma
Osteosarcoma
Parosteal osteosarcoma
Periosteal osteosarcoma
High-grade surface osteosarcoma
Secondary osteosarcoma
Fibrogenic tumours
Desmoplastic fibroma of bone
Fibrosarcoma of bone
Vascular tumours of bone
Haemangioma of bone
Epithelioid haemangioma of bone
Epithelioid haemangioendothelioma of bone
Angiosarcoma of bone
Osteoclastic giant cell-rich tumours
Aneurysmal bone cyst
Giant cell tumour of bone
Non-ossifying fibroma
Notochordal tumours
Benign notochordal cell tumour
Conventional chordoma
Dedifferentiated chordoma
Poorly differentiated chordoma
Other mesenchymal tumours of bone
Chondromesenchymal hamartoma of chest wall
Osteofibrous dysplasia
Adamantinoma of long bones
Simple bone cyst
Fibrocartilaginous mesenchymoma
Fibrous dysplasia
Lipoma and hibernoma of bone
Leiomyosarcoma of bone
Undifferentiated pleomorphic sarcoma
Bone metastases
Haematopoietic neoplasms of bone
Solitary plasmacytoma of bone
Primary non-Hodgkin lymphoma of bone
Langerhans cell histiocytosis
Erdheim-Chester disease
Rosai-Dorfman disease
5. Genetic tumour syndromes of soft tissue and bone
Genetic tumour syndromes of soft tissue and bone: Introduction
Enchondromatosis
Li-Fraumeni syndrome
McCune-Albright syndrome
Multiple osteochondromas
Neurofibromatosis type 1
Rothmund-Thomson syndrome
Werner syndrome