- Skin tumours (4th ed.)
- 1. Foreword
WHO Classification of Tumours: Editors
Introduction to website version
- 2. Keratinocytic/epidermal tumours
Introduction
Carcinomas
Basal cell carcinoma
Nodular basal cell carcinoma
Superficial basal cell carcinoma
Micronodular basal cell carcinoma
Infiltrating basal cell carcinoma
Sclerosing/morphoeic basal cell carcinoma
Basosquamous carcinoma
Pigmented basal cell carcinoma
Basal cell carcinoma with sarcomatoid differentiation
Basal cell carcinoma with adnexal differentiation
Fibroepithelial basal cell carcinoma
Squamous cell carcinoma
Squamous cell carcinoma
Keratoacanthoma
Acantholytic squamous cell carcinoma
Spindle cell squamous cell carcinoma
Verrucous squamous cell carcinoma
Adenosquamous carcinoma
Clear cell squamous cell carcinoma
Other (uncommon) variants
Squamous cell carcinoma in situ (Bowen disease)
Merkel cell carcinoma
Carcinoma precursors and benign simulants
Premalignant keratoses
Actinic keratosis
Arsenical keratosis
PUVA keratosis
Verrucae
Verruca vulgaris
Verruca plantaris
Verruca plana
Benign acanthomas/keratoses
Seborrhoeic keratosis
Solar lentigo
Lichen planus–like keratosis
Clear cell acanthoma
Large cell acanthoma
Warty dyskeratoma
Other benign keratoses
- 3. Melanocytic tumours
Introduction
Melanocytic tumour classification and the pathway concept of melanoma pathogenesis
Genomic landscape of melanoma
Melanocytic tumours in intermittently sun-exposed skin
Low-CSD melanoma (superficial spreading melanoma)
Simple lentigo and lentiginous melanocytic naevus
Junctional, compound, and dermal naevi
Dysplastic naevus
Naevus spilus
Special-site naevi (of the breast, axilla, scalp, and ear)
Halo naevus
Meyerson naevus
Recurrent naevus
Deep penetrating naevus and melanocytoma
Pigmented epithelioid melanocytoma
Combined naevus, including combined BAP1-inactivated naevus / melanocytoma
Melanocytic tumours in chronically sun-exposed skin
Lentigo maligna melanoma
Desmoplastic melanoma
Spitz tumours
Malignant Spitz tumour (Spitz melanoma)
Spitz naevus
Pigmented spindle cell naevus (Reed naevus)
Melanocytic tumours in acral skin
Acral melanoma
Acral naevus
Genital and mucosal melanocytic tumours
Mucosal melanomas (genital, oral, sinonasal)
Genital naevus
Melanocytic tumours arising in blue naevus
Melanoma arising in blue naevus
Blue naevus and cellular blue naevus
Mongolian spot
Naevus of Ito and naevus of Ota
Melanocytic tumours arising in congenital naevi
Melanoma arising in giant congenital naevus
Congenital melanocytic naevus
Proliferative nodules in congenital melanocytic naevus
Ocular melanocytic tumours
Uveal melanoma
Conjunctival melanoma
Conjunctival melanocytic intraepithelial neoplasia/primary acquired melanosis
Conjunctival naevus
Nodular, naevoid, and metastatic melanomas
Nodular melanoma
Naevoid melanoma
Metastatic melanoma
- 4. Appendageal tumours
Introduction
Malignant tumours with apocrine and eccrine differentiation
Adnexal adenocarcinoma not otherwise specified
Microcystic adnexal carcinoma
Porocarcinoma
Malignant neoplasms arising from spiradenoma, cylindroma, or spiradenocylindroma
Malignant mixed tumour
Hidradenocarcinoma
Mucinous carcinoma
Endocrine mucin-producing sweat gland carcinoma
Digital papillary adenocarcinoma
Adenoid cystic carcinoma
Apocrine carcinoma
Squamoid eccrine ductal carcinoma
Syringocystadenocarcinoma papilliferum
Secretory carcinoma
Cribriform carcinoma
Signet-ring cell/histiocytoid carcinoma
Benign tumours with apocrine and eccrine differentiation
Hidrocystoma/cystadenoma
Syringoma
Poroma
Syringofibroadenoma
Hidradenoma
Spiradenoma
Cylindroma
Tubular adenoma
Syringocystadenoma papilliferum
Mixed tumour
Myoepithelioma
Malignant tumours with follicular differentiation
Pilomatrical carcinoma
Proliferating trichilemmal tumour
Trichoblastic carcinoma/carcinosarcoma
Trichilemmal carcinoma
Benign tumours with follicular differentiation
Trichoblastoma
Pilomatricoma
Trichilemmoma
Trichofolliculoma
Pilar sheath acanthoma
Tumour of the follicular infundibulum
Melanocytic matricoma
Spindle cell–predominant trichodiscoma
Tumours with sebaceous differentiation
Sebaceous carcinoma
Sebaceous adenoma
Sebaceoma
Site-specific tumours
Mammary Paget disease
Extramammary Paget disease
Adenocarcinoma of anogenital mammary-like glands
Hidradenoma papilliferum
Fibroadenoma and phyllodes tumour of anogenital mammary-like glands
- 5. Tumours of haematopoietic and lymphoid origin
Introduction
Mycosis fungoides
Variants of mycosis fungoides
Folliculotropic mycosis fungoides
Granulomatous slack skin
Pagetoid reticulosis
Sezary syndrome
Primary cutaneous CD30+ T-cell lympho proliferative disorders
Lymphomatoid papulosis
Primary cutaneous anaplastic large cell lymphoma
Cutaneous adult T-cell leukaemia/lymphoma
Subcutaneous panniculitis-like T-cell lymphoma
Cutaneous manifestations of chronic active EBV infection
Extranodal NK/T-cell lymphoma, nasal type
Primary cutaneous peripheral T-cell lymphomas, rare subtypes
Primary cutaneous gamma-delta T-cell lymphoma
Primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma
Primary cutaneous acral CD8+ T-cell lymphoma
Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder
Secondary cutaneous involvement in T-cell lymphomas and leukaemias
Systemic anaplastic large cell lymphoma
Angioimmunoblastic T-cell lymphoma
T-cell prolymphocytic leukaemia
Primary cutaneous marginal zone (MALT) lymphoma
Primary cutaneous follicle centre lymphoma
Primary cutaneous diffuse large B-cell lymphoma, leg type
Intravascular large B-cell lymphoma
EBV-positive mucocutaneous ulcer
Lymphomatoid granulomatosis
Cutaneous involvement in primarily extracutaneous B-cell lymphomas and leukaemias
Mantle cell lymphoma
Burkitt lymphoma
Chronic lymphocytic leukaemia/small lymphocytic lymphoma
T-lymphoblastic and B-lymphoblastic leukaemia/lymphoma
Blastic plasmacytoid dendritic cell neoplasm
Cutaneous involvement in myeloid leukaemia
Cutaneous mastocytosis
Introduction to histiocytic and dendritic cell neoplasms
Langerhans cell histiocytosis
Indeterminate cell histiocytosis/indeterminate dendritic cell tumour
Rosai-Dorfman disease
Juvenile xanthogranuloma
Erdheim–Chester disease
Reticulohistiocytosis
- 6. Soft tissue tumours
Introduction
Adipocytic tumours
Atypical lipomatous tumour
Pleomorphic liposarcoma
Lipoma
Spindle cell/pleomorphic lipoma
Angiolipoma
Naevus lipomatosus superficialis
Fibroblastic, myofibroblastic, and fibrohistiocytic tumours
Myxoinflammatory fibroblastic sarcoma
Dermatofibrosarcoma protuberans and variants
Plexiform fibrohistiocytic tumour
Superficial fibromatosis
Dermatofibroma (fibrous histiocytoma) and variants
Epithelioid fibrous histiocytoma
Fibromas
Fibroma of tendon sheath
Calcifying aponeurotic fibroma
Sclerotic fibroma
Nuchal-type fibroma
Gardner fibroma
Pleomorphic fibroma
Elastofibroma
Collagenous fibroma
Superficial acral fibromyxoma
Cutaneous myxoma
Dermatomyofibroma
Myofibroma and myofibromatosis
Plaque-like CD34+ dermal fibroma
Nodular fasciitis
Smooth muscle tumours
Cutaneous leiomyomas and variants
Cutaneous leiomyosarcoma (atypical smooth muscle tumour)
(Myo)pericytic tumours
Glomus tumour and variants
Myopericytoma and variants
Angioleiomyoma
Vascular tumours
Cutaneous angiosarcoma
Haemangioendotheliomas
Composite haemangioendothelioma
Kaposiform haemangioendothelioma
Pseudomyogenic haemangioendothelioma
Retiform haemangioendothelioma
Epithelioid haemangioendothelioma
Kaposi sarcoma
Atypical vascular lesion
Cutaneous epithelioid angiomatous nodule
Haemangiomas
Cherry haemangioma
Sinusoidal haemangioma
Microvenular haemangioma
Hobnail haemangioma
Glomeruloid haemangioma
Spindle cell haemangioma
Epithelioid haemangioma
Tufted haemangioma
Angiokeratoma
Infantile haemangioma
Congenital non-progressive haemangiomas: rapidly involuting congenital haemangioma and non-involuting congenital haemangioma
Lobular capillary haemangioma
Verrucous venous malformation
Arteriovenous malformation
Lymphangioma (superficial lymphatic malformation)
Neural tumours
Neurofibroma and variants
Solitary circumscribed neuroma
Dermal nerve sheath myxoma
Perineurioma
Granular cell tumour
Schwannoma
Malignant peripheral nerve sheath tumour
Tumours of uncertain differentiation
Atypical fibroxanthoma and variants
Pleomorphic dermal sarcoma
Myxofibrosarcoma
Epithelioid sarcoma
Dermal clear cell sarcoma
Ewing sarcoma
Primitive non-neural granular cell tumour
Cellular neurothekeoma
- 7. Inherited tumour syndromes associated with skin malignancies
Introduction
Familial melanoma
Xeroderma pigmentosum
Naevoid basal cell carcinoma syndrome (Gorlin syndrome)
Carney complex
BAP1 tumour predisposition syndrome
Muir-Torre syndrome