- Haematolymphoid Tumours (5th ed.)
- 1. Forewords and Introductions
General Introduction
ICCR datasets: Haemopoietic
- 2. Myeloid proliferations and neoplasms
Myeloid precursor lesions
Clonal Haematopoiesis
Introduction
Clonal haematopoiesis
Clonal cytopenias of undetermined significance
Myeloproliferative neoplasms
Myeloproliferative neoplasms
Introduction
Chronic myeloid leukaemia
Chronic neutrophilic leukaemia
Chronic eosinophilic leukaemia
Polycythaemia vera
Essential thrombocythaemia
Primary myelofibrosis
Juvenile myelomonocytic leukaemia
Myeloproliferative neoplasm, NOS
Mastocytosis
Introduction
Cutaneous mastocytosis
Systemic mastocytosis
Mast cell sarcoma
Myelodysplastic neoplasms
Introduction
Myelodysplastic neoplasms, with defining genetic abnormalities
Myelodysplastic neoplasm with low blasts and 5q deletion
Myelodysplastic neoplasm with low blasts and SF3B1 mutation
Myelodysplastic neoplasm with biallelic TP53 inactivation
Myelodysplastic neoplasms, morphologically defined
Myelodysplastic neoplasm with low blasts
Myelodysplastic neoplasm, hypoplastic
Myelodysplastic neoplasm with increased blasts
Myelodysplastic neoplasms of childhood
Childhood myelodysplastic neoplasm with low blasts
Childhood myelodysplastic neoplasm with increased blasts
Myelodysplastic/myeloproliferative neoplasms
Introduction
Chronic myelomonocytic leukaemia
Myelodysplastic/myeloproliferative neoplasm with neutrophilia
Myelodysplastic/myeloproliferative neoplasm with SF3B1 mutation and thrombocytosis
Myelodysplastic/myeloproliferative neoplasm, NOS
Acute myeloid leukaemia
Introduction
Acute myeloid leukaemia with defining genetic abnormalities
Acute promyelocytic leukaemia with PML::RARA fusion
Acute myeloid leukaemia with RUNX1::RUNX1T1 fusion
Acute myeloid leukaemia with CBFB::MYH11 fusion
Acute myeloid leukaemia with DEK::NUP214 fusion
Acute myeloid leukaemia with RBM15::MRTFA fusion
Acute myeloid leukaemia with BCR::ABL1 fusion
Acute myeloid leukaemia with KMT2A rearrangement
Acute myeloid leukaemia with MECOM rearrangement
Acute myeloid leukaemia with NUP98 rearrangement
Acute myeloid leukaemia with NPM1 mutation
Acute myeloid leukaemia with CEBPA mutation
Acute myeloid leukaemia, myelodysplasia-related
Acute myeloid leukaemia with other defined genetic alterations
Acute myeloid leukaemia, defined by differentiation
Acute myeloid leukaemia with minimal differentiation
Acute myeloid leukaemia without maturation
Acute myeloid leukaemia with maturation
Acute basophilic leukaemia
Acute myelomonocytic leukaemia
Acute monocytic leukaemia
Acute erythroid leukaemia
Acute megakaryoblastic leukaemia
Myeloid sarcoma
Myeloid sarcoma
Myeloid neoplasms, secondary
Myeloid neoplasms and proliferations associated with antecedent or predisposing conditions
Introduction
Myeloid neoplasm post cytotoxic therapy
Myeloid neoplasms associated with germline predisposition
Myeloid proliferations associated with Down syndrome
Myeloid/lymphoid neoplasms
Myeloid/lymphoid neoplasms with eosinophilia and defining gene rearrangement
Introduction
Myeloid/lymphoid neoplasm with PDGFRA rearrangement
Myeloid/lymphoid neoplasm with PDGFRB rearrangement
Myeloid/lymphoid neoplasm with FGFR1 rearrangement
Myeloid/lymphoid neoplasm with JAK2 rearrangement
Myeloid/lymphoid neoplasm with FLT3 rearrangement
Myeloid/lymphoid neoplasm with ETV6::ABL1 fusion
Myeloid/lymphoid neoplasms with other tyrosine kinase fusion genes
Acute leukaemias of mixed or ambiguous lineage
Introduction
Acute leukaemia of ambiguous lineage with defining genetic abnormalities
Mixed-phenotype acute leukaemia with BCR::ABL1 fusion
Mixed-phenotype acute leukaemia with KMT2A rearrangement
Acute leukaemia of ambiguous lineage with other defined genetic alterations
Acute leukaemia of ambiguous lineage, immunophenotypically defined
Mixed-phenotype acute leukaemia, B/myeloid
Mixed-phenotype acute leukaemia, T/myeloid
Mixed-phenotype acute leukaemia, rare types
Acute leukaemia of ambiguous lineage, NOS
Acute undifferentiated leukaemia
- 3. Histiocytic/Dendritic cell neoplasms
Introduction
Plasmacytoid dendritic cell neoplasms
Plasmacytoid dendritic cell neoplasms
Mature plasmacytoid dendritic cell proliferation associated with myeloid neoplasm
Blastic plasmacytoid dendritic cell neoplasm
Langerhans cell and other dendritic cell neoplasms
Langerhans cells neoplasms
Langerhans cell histiocytosis
Langerhans cell sarcoma
Other dendritic cell neoplasms
Indeterminate dendritic cell tumour
Interdigitating dendritic cell sarcoma
Histiocyte/macrophage neoplasms
Histiocytic neoplasms
Juvenile xanthogranuloma
Erdheim-Chester disease
Rosai-Dorfman Disease
ALK-positive histiocytosis
Histiocytic sarcoma
- 4. B-cell lymphoid proliferations and lymphomas
Introduction to B-cell lymphoproliferative disorders and neoplasms
Tumour like lesions with B-cell predominance
Introduction
Reactive B-cell rich lymphoid proliferations that can mimic lymphoma
IgG4-related disease
Unicentric Castleman disease
Idiopathic multicentric Castleman disease
KSHV/HHV8-associated multicentric Castleman disease
Precursor B-cell neoplasms
B-lymphoblastic leukaemias/lymphomas
Introduction
B-lymphoblastic leukaemia/lymphoma
B-lymphoblastic leukaemia/lymphoma with high hyperdiploidy
B-lymphoblastic leukaemia/lymphoma with hypodiploidy
B-lymphoblastic leukaemia/lymphoma with iAMP21
B-lymphoblastic leukaemia/lymphoma with BCR::ABL1 fusion
B-lymphoblastic leukaemia/lymphoma with BCR::ABL1-like features
B lymphoblastic leukaemia/lymphoma with KMT2A rearrangement
B lymphoblastic leukaemia/lymphoma with ETV6::RUNX1 fusion
B-lymphoblastic leukaemia/lymphoma with ETV6::RUNX1-like features
B lymphoblastic leukaemia/lymphoma with TCF3::PBX1 fusion
B lymphoblastic leukaemia/lymphoma with IGH::IL3 fusion
B lymphoblastic leukaemia/lymphoma with TCF3::HLF fusion
B-lymphoblastic leukaemia/lymphoma with other defined genetic alterations
B-lymphoblastic leukaemia/lymphoma, NOS
Mature B-cell neoplasms
Pre-neoplastic and neoplastic small lymphocytic proliferations
Introduction
Monoclonal B-cell lymphocytosis
Chronic lymphocytic leukaemia/small lymphocytic lymphoma
Splenic B-cell lymphomas and leukaemias
Introduction
Hairy cell leukaemia
Splenic marginal zone lymphoma
Splenic diffuse red pulp small B-cell lymphoma
Splenic B-cell lymphoma/leukaemia with prominent nucleoli
Lymphoplasmacytic lymphoma
Lymphoplasmacytic lymphoma
Marginal zone lymphoma
Introduction
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue
Primary cutaneous marginal zone lymphoma
Nodal marginal zone lymphoma
Paediatric nodal marginal zone lymphoma
Follicular lymphoma
Introduction
In situ follicular B-cell neoplasm
Follicular lymphoma
Paediatric-type follicular lymphoma
Duodenal-type follicular lymphoma
Cutaneous follicle centre lymphoma
Primary cutaneous follicle centre lymphoma
Mantle cell lymphoma
Introduction
In situ mantle cell neoplasm
Mantle cell lymphoma
Leukaemic non-nodal mantle cell lymphoma
Transformations of indolent B-cell lymphomas
Introduction
Transformations of indolent B-cell lymphomas
Large B-cell lymphomas
Introduction
Diffuse large B-cell lymphoma, NOS
T-cell/histiocyte-rich large B-cell lymphoma
Diffuse large B-cell lymphoma / high grade B-cell lymphoma with MYC and BCL2 rearrangements
ALK-positive large B-cell lymphoma
Large B-cell lymphoma with IRF4 rearrangement
High grade B-cell lymphoma with 11q aberrations
Lymphomatoid granulomatosis
EBV-positive diffuse large B-cell lymphoma
Diffuse large B-cell lymphoma associated with chronic inflammation
Fibrin-associated large B-cell lymphoma
Fluid overload-associated large B-cell lymphoma
Plasmablastic lymphoma
Primary large B-cell lymphoma of immune-privileged sites
Primary cutaneous diffuse large B-cell lymphoma, leg type
Intravascular large B-cell lymphoma
Primary mediastinal large B-cell lymphoma
Mediastinal grey zone lymphoma
High-grade B-cell lymphoma, NOS
Burkitt lymphoma
Burkitt lymphoma
KSHV/HHV8-associated B-cell lymphoid proliferations and lymphomas
Introduction
Primary effusion lymphoma
KSHV/HHV8-positive diffuse large B-cell lymphoma
KSHV/HHV8-positive germinotropic lymphoproliferative disorder
Lymphoid proliferations and lymphomas associated with immune deficiency and dysregulation
Introduction
Hyperplasias arising in immune deficiency/dysregulation
Polymorphic lymphoproliferative disorders arising in immune deficiency / dysregulation
EBV-positive mucocutaneous ulcer
Lymphomas arising in immune deficiency / dysregulation
Inborn error of immunity-associated lymphoid proliferations and lymphomas
Hodgkin lymphoma
Introduction
Classic Hodgkin lymphoma
Nodular lymphocyte predominant Hodgkin lymphoma
Plasma cell neoplasms and other diseases with paraproteins
Introduction
Monoclonal gammopathies
Cold agglutinin disease
IgM monoclonal gammopathy of undetermined significance
Non-IgM monoclonal gammopathy of undetermined significance
Monoclonal gammopathy of renal significance
Diseases with monoclonal immunoglobulin deposition
Immunoglobulin-related (AL) amyloidosis
Monoclonal immunoglobulin deposition disease
Heavy chain diseases
Introduction
Mu heavy chain disease
Gamma heavy chain disease
Alpha heavy chain disease
Plasma cell neoplasms
Introduction
Plasmacytoma
Plasma cell myeloma / multiple myeloma
Plasma cell neoplasms with associated paraneoplastic syndrome
- 5. T-cell and NK-cell lymphoid proliferations and lymphomas
Introduction
Tumour-like lesions with T-cell predominance
Kikuchi-Fujimoto disease
Autoimmune lymphoproliferative syndrome
Indolent T-lymphoblastic proliferation
Precursor T-cell neoplasms
T-lymphoblastic leukaemia / lymphoma
T-lymphoblastic leukaemia / lymphoma, NOS
Early T-precursor lymphoblastic leukaemia / lymphoma
Mature T-cell and NK-cell neoplasms
Mature T-cell and NK-cell leukaemias
Introduction
T-prolymphocytic leukaemia
T-large granular lymphocytic leukaemia
NK-large granular lymphocytic leukaemia
Adult T-cell leukaemia/lymphoma
Sezary syndrome
Aggressive NK-cell leukaemia
Primary cutaneous T-cell lymphoid proliferations and lymphomas
Introduction to primary cutaneous T-cell neoplasms
Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorder
Primary cutaneous acral CD8-positive T-cell lymphoproliferative disorder
Mycosis fungoides
Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Lymphomatoid papulosis
Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Primary cutaneous anaplastic large cell lymphoma
Subcutaneous panniculitis-like T-cell lymphoma
Primary cutaneous gamma/delta T-cell lymphoma
Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma
Primary cutaneous peripheral T-cell lymphoma, NOS
Intestinal T-cell and NK-cell lymphoid proliferations and lymphomas
Introduction
Indolent T-cell lymphoma of the gastrointestinal tract
Indolent NK-cell lymphoproliferative disorder of the gastrointestinal tract
Enteropathy-associated T-cell lymphoma
Monomorphic epitheliotropic intestinal T-cell lymphoma
Intestinal T-cell lymphoma, NOS
Hepatosplenic T-cell lymphoma
Hepatosplenic T-cell lymphoma
Anaplastic large cell lymphoma
Introduction
ALK-positive anaplastic large cell lymphoma
ALK-negative anaplastic large cell lymphoma
Breast implant-associated anaplastic large cell lymphoma
Nodal T-follicular helper (TFH) cell lymphoma
Introduction
Nodal TFH cell lymphoma, angioimmunoblastic-type
Nodal TFH cell lymphoma, follicular-type
Nodal TFH cell lymphoma, NOS
Other peripheral T-cell lymphomas
Peripheral T-cell lymphoma, NOS
EBV-positive NK-cell and T-cell lymphomas
EBV-positive nodal T- and NK-cell lymphoma
Extranodal NK/T-cell lymphoma
EBV-positive T-cell and NK-cell lymphoid proliferations and lymphomas of childhood
Introduction
Severe mosquito bite allergy
Hydroa vacciniforme lymphoproliferative disorder
Systemic chronic active EBV disease
Systemic EBV-positive T-cell lymphoma of childhood
- 6. Stroma-derived neoplasms of lymphoid tissues
Introduction
Mesenchymal dendritic cell neoplasms
Follicular dendritic cell neoplasms
Follicular dendritic cell sarcoma
EBV-positive inflammatory follicular dendritic cell sarcoma
Fibroblastic reticular cell tumour
Myofibroblastic tumours
Myofibroblastic tumour
Intranodal palisaded myofibroblastoma
Spleen-specific vascular-stromal tumours
Splenic vascular-stromal tumours
Littoral cell angioma
Splenic hamartoma
Sclerosing angiomatoid nodular transformation (SANT) of spleen
- 7. Genetic tumour syndromes
Introduction
Fanconi anaemia
Bloom syndrome
Ataxia-telangiectasia syndrome
RASopathies