#1 Boston–Kyoto Surgical Pathology Update 2013 Slide Seminar Thumbnails originally http://www2.massgeneral.org/pathology/hms/Kyoto13.htm (deleted) |
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Insular/trabecular patterns, occasional mitoses, nuclear features different from typical papillary carcinoma.
Numerous psammoma bodies and morule formation, in Hashimoto thyroiditis-like dense lymphocytic and sclerotic background
Comedo necrosis and numerous mitoses in basaloid cells
The lesion contains floret cells that may mimic pleomorphic lipoma and atypical lipomatous tumor.
A hemosiderotic fibrohistiocytic lipomatous lesion, or hemosiderotic fibrolipomatous tumor.
Consistent t(1;10) with rearrangements of TGFBR3 and MGEA5 in both myxoinflammatory fibroblastic sarcoma and hemosiderotic fibrolipomatous tumor.
Bland spindle cells with CD34 and EMA positivity
Large cells were Megakryocytic cells, as seen in original myeloproliferative disorders.
All melanoma markers including S-100 were negative ("dedifferentiated"). BRAF+ as was previous malignant melanoma of the skin.